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https://journals.lww.com/jasn/fulltext/2024/11000/cover_image.24.aspx
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https://journals.lww.com/jasn/fulltext/2024/11000/table_of_contents.25.aspx
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The discovery of the aquaporin family of water channels has provided a molecular counterpart to the movement of water across biological membranes. The distribution of aquaporins in specific cell...
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https://journals.lww.com/jasn/fulltext/2024/11000/correction__hnf1b_alters_an_evolutionarily.23.aspx
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Key Points The vascular endothelial growth factor B inhibitor CSL346 (8 or 16 mg/kg q4w) did not reduce urinary albumin-creatinine ratio at week 16 versus placebo in patients with type 2 diabete...
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Key Points The predictive performance of an African ancestry–specific polygenic risk score (PRS) was comparable to a European ancestry–derived PRS for kidney traits.However, multi-ancestry P...
Key Points Among 4173 children with AKI, 18% had major adverse kidney events (death, kidney failure, or CKD) during a median 10-year follow-up.AKI survivors were at 2–4 times higher risk of ma...
Key Points This study developed a urine acid/base score to assess tubular acid excretion capacity and identify early acid retention in CKD.The results show that early signs of acid retention (a ...
Key Points Renovascular disease impairs the capacity of human adipose tissue–derived mesenchymal stem/stromal cells to repair ischemic murine kidneys.miR-378h modulated the capacity of renovas...
Key Points Ketogenic diet can change the metabolism in the body and helped restore the function of altered pathways in nephropathic cystinosis.Ketogenic diet had significant benefits for prevent...
Key Points Bile acids activate the epithelial Na+ channel (ENaC), which may lead to subsequent fluid retention in liver disease.Bile duct ligation with spironolactone increased ENaC-dependent Na...
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Key Points Angiotensin II–type-1a-receptor in the distal convoluted tubule (DCT) plays a role in regulating sodium transport in the DCT.Angiotensin II–type-1a-receptor in the DCT plays a rol...