showing that the biological effects have similarities. Now, a team clears the air and reports that DNA methylation changes in vapers’ oral cells resemble those found in smokers, which suggests...
has been touted as a safer alternative to smoking, but some recent studies are showing that the biological effects have similarities. Now, a team clears the air and reports
methyltransferases mildly increases viral replication, the knockdown of the m5C methyltransferase NSUN2 prompts a reduction in m5C levels on viral RNA and enhances viral
https://epigenie.com/spotlight-on-emerging-rna-methylation-analysis-techniques/#comment-24067
life cycle; however, they realized that the relevance of the all-important 5-methylcytosine (m5C) RNA modification remained somewhat unexplored for SARS-CoV-2 and viruses in general. This
Eine halbwegs verständliche Beschreibung findet man hier: „Inside Job: dCas9 Hijacks Endogenous Chromatin Machinery to Modulate Gene Expression“
to hunt down more. They developed Chrom-seq, which combines well-established reader proteins with a proximity biotinylation strategy to grab onto and isolate lncRNAs that are close to histone mo...
“Low Input” version of itChIP functions well for the analysis of permissive histone marks (H3K4me3), repressive histone marks (H3K27me3), and non-histone DNA-binding proteins (p300, RNA Poly...
desire for increased resolution, a talented team is using histone readers to more clearly see which long noncoding RNAs (lncRNAs) interact with particular histone modifications. Their method, ca...
https://epigenie.com/a-novel-lncrna-plays-cat-and-maos-with-aggressive-behaviors/#comment-23726
ChIP-Seq showed that the knock-downs affect most of the H3K27me3 sites in wild-type cells, so the lncRNAs are needed to preserve this modification
https://epigenie.com/the-tn5-transposase-takes-single-cell-chip-seq-to-the-next-level/#comment-23725
fine details up close. Inspired by our desire for increased resolution, a talented team is using histone readers to more clearly see which long noncoding RNAs (lncRNAs) interact with particular ...